C
Name  CADASIL
Related to/Also known as

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy, Cadasil

Symptoms of CADASIL

Patient Information leaflet (Cambridge University Hospitals NHS Foundation Trust): 
https://www.cambridgestroke.com/userfiles/CADASILLeaflet1July2020A4.pdf

"CADASIL is an abbreviation for a long name describing a rare hereditary form of stroke (Cerebral AutosomalDominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy). The disease usually presents with multiple small strokes, but migraine can also be a prominent feature. CADASIL is a genetic condition caused by a small abnormality (mutation) in a gene called NOTCH3."

Sourcehttps://www.cambridgestroke.com/cadasil.php

"CADASIL (Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy) is an inherited form of cerebrovascular disease that occurs when the thickening of blood vessel walls blocks the flow of blood to the brain. The disease primarily affects small blood vessels in the white matter of the brain. A mutation in the Notch3 gene alters the muscular walls in these small arteries. CADASIL is characterized by migraine headaches and multiple strokes progressing to dementia."

Source: https://www.ninds.nih.gov/Disorders/All-Disorders/CADASIL-Information-Page

Useful national contacts

Cadasil Support UK
Link opens in new window www.cadasilsupportuk.co.uk
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Cadasil Research Cambrige
Link opens in new window www.cambridgestroke.com/cadasil.php

Stroke Association
Link opens in new window www.stroke.org.uk

Children & young people CADASIL (Child Neurlogy Foundation, U.S.A.)
Link opens in new window www.childneurologyfoundation.org/disorder/cadasil
Online resources

CADASIL Informaton Page (U.S. National Institute for Neurological Disorders and Stroke)
Link opens in new window www.ninds.nih.gov/Disorders/All-Disorders/CADASIL-Information-Page

CADASIL (U.S. Genetic and Rare Disease Information Center)
Link opens in new window https://rarediseases.info.nih.gov/diseases/1049/cadasil

CADASIL (U.S. National Organization for Rare Disorders)
Link opens in new window https://rarediseases.org/rare-diseases/cadasil

CADASIL Foundation (U.S.A.)
Link opens in new window http://cadasilfoundation.org/

Coronavirus - information for people with neurological problems (Brain & Spine Foundation)
Link opens in new window www.brainandspine.org.uk/coronavirus-covid-19

 Living with a condition (The Brain Charity)

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