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Landau-Kleffner Syndrome

Name	Landau-Kleffner Syndrome
Related to/Also known as	Acquired Epileptic Aphasia
Symptoms of Landau-Kleffner Syndrome	Landau-Kleffner Syndrome is a rare form of epilepsy that affects only children. It is characterised by severe language problems (aphasia). Symptoms may also include seizures.
Types
Useful national contacts	Contact A Family Freephone helpline (UK only): 0808 808 3555 cafamily.org.uk Cerebra, UK charity for children with neurological conditions http://w3.cerebra.org.uk Telephone 01267 244200 Email This email address is being protected from spambots. You need JavaScript enabled to view it. Find your local support: https://tinyurl.com/ycl8djhy
Online resources	Landau Kleffner Syndrome (Epilepsy Action) https://tinyurl.com/ybkll5cy Landau-Kleffner Syndrome Information Page (U.S. National Institute of Neurological Disorders and Stroke) https://tinyurl.com/b5hu4
Our resources	The library at The Brain Charity has a range of resources on Landau Kleffner Syndrome and on a wide range of disability-related issues.

Leigh Syndrome

Name	Leigh Syndrome
Related to/Also known as	Leigh's Disease Leigh's Syndrome Necrotizing encephalopathy Subacute Necrotizing Encephalomyelopathy (SNEM) Mitochondrial disease see also Rare Conditions
Symptoms of Leigh Syndrome	Leigh Syndrome is a rare, inherited, early-onset degenerative disorder with many different symptoms. This is a disease of the mitochondria, which provide energy for nerve cells in the brain and muscles.
Types	X-linked Leigh Disease
Useful national contacts	The Leigh Network leighnetwork.tumblr.com Email This email address is being protected from spambots. You need JavaScript enabled to view it. Climb (Children Living with Inherited Metabolic Diseases) www.climb.org.uk Freephone 0800 652 3181 The Rare Mitochondrial Disease Service for Adults and Children (NHS) www.mitochondrialncg.nhs.uk
News and events
Online resources	Leigh's Disease Information Page (U.S. National Institute for Neurological Disorders and Stroke) https://tinyurl.com/yy7b88
Our resources	The library at The Brain Charity has a range of resources on Leigh's Disease and on a wide range of disability-related issues.

Leukodystrophy

Name	Leukodystrophy
Related to/Also known as	Adrenoleukodystrophy (ALD) Lorenzo's Oil disease
Symptoms of Leukodystrohy	The Leukodystrophies are a group of genetic disorders, which are generally diagnosed in childhood. Caused by a breakdown of the myelin sheath surrounding nerve cells in the brain. There are several forms, and the most common symptoms are a slowdown in mental and physical development
Types	Metachromatic leukodystrohy Refsum's disease Adrenoleukodysrophy Krabbe's disease Phenylketonuria Canavan disease Pelizaeus-Merzbacher disease Alexander's disease Cerebrotendinous Zxanthomatosis (CTX) Juvenile HD (also called Westphal variant or akinetic-rigid HD) develops before the age of 20, progresses rapidly, and produces muscle rigidity in which the patient moves little, if at all (akinesia).
Useful national contacts	Climb National Information Centre for Metabolic Diseases www.climb.org.uk Tel: 0800 652 3181 (Open 10am - 4pm) Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Online resources	Leukodystrophy Information Page (U.S. National Institute of Neurological Disorders and Stroke) https://tinyurl.com/2clyexs
Our resources	The library at The Brain Charity has a range of resources on Leukodystrohy and on a wide range of disability-related issues.

Lissencephaly

Name	Lissencephaly
Related to/Also known as
Symptoms of Lissencephaly	Lissencephaly is used as an 'umbrella' term to describe a range of disorders where the whole or parts of the surface of the brain appear smooth.
Types	Classical Lissencephaly Cobblestone Lissencephaly
Useful national contacts	Lissencephaly Contact Group c/o Contact a Family Web www.cafamily.org.uk Tel. 0808 808 3555
Online resources	Lissencephaly Information page (U.S. National Institute of Neurological Disorders and Stroke) https://tinyurl.com/9brylb
Our resources	The library at The Brain Charity has a range of resources on Lissencephaly and on a wide range of disability-related issues.

Lupus

Name	Lupus
	See Systemic Lupus Erythematosus (SLE)

Lyme Disease

Name	Lyme Disease
Related to/Also known as	Borreliosis
Symptoms of Lyme Disease	Lyme Disease is an infectious disease caused by the bacterium Borrelia Burgdorferi. The disease is transmitted to humans by the bite of an infected tick. If left untreated it can affect the skin, heart, nervous system and joints.
Types
Useful national contacts	Lyme Disease Action www.lymediseaseaction.org.uk
Online resources	Lyme disease (NHS Choices) https://tinyurl.com/y8dram83 Lyme disease (Facial Palsy UK) https://tinyurl.com/y9rkwv3y UK Tick Threat Map (The Big Tick Project) https://tinyurl.com/ycx48khu
News and events	"Ignorance of tick-borne Lyme disease 'costing lives'" (BBC News, May 2013) www.bbc.co.uk/news/health-22468181
Our resources	The library at The Brain Charity has a range of resources on Lyme Disease and on a wide range of disability-related issues.